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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
+19.63%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$6.55B
AUM Growth
+$1.04B
Cap. Flow
+$118M
Cap. Flow %
1.81%
Top 10 Hldgs %
51.69%
Holding
171
New
48
Increased
43
Reduced
20
Closed
19

Top Buys

Rank Stock Value
1
CNC icon
Centene
CNC
+$177M
2
BMY icon
Bristol-Myers Squibb
BMY
+$109M
3
IONS icon
Ionis Pharmaceuticals
IONS
+$96.7M
4
INSP icon
Inspire Medical Systems
INSP
+$91.9M
5
COGT icon
Cogent Biosciences
COGT
+$76M

Top Sells

Rank Stock Value
1
OSCR icon
Oscar Health
OSCR
+$250M
2
INDV icon
Indivior Pharmaceuticals
INDV
+$74.9M
3
BAX icon
Baxter International
BAX
+$47.7M
4
IDYA icon
IDEAYA Biosciences
IDYA
+$42.6M
5
UTHR icon
United Therapeutics
UTHR
+$38.6M

Sector Composition

Rank Sector Weight
1 Healthcare 91.55%
2 Real Estate 0.38%
3 Financials 0.07%
4 Consumer Staples 0.07%
5 Consumer Discretionary 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
IQV icon
151
IQVIA
IQV
$35.6B
– –
-1,623
Closed -$256K
LQDA icon
152
Liquidia Corp
LQDA
$7.51B
– –
-1,616,778
Closed -$20.1M
LUNG icon
153
Pulmonx
LUNG
$51.5M
– –
-1,890,000
Closed -$4.9M
MEDP icon
154
Medpace
MEDP
$16.5B
– –
-736
Closed -$231K
MREO
155
Mereo BioPharma
MREO
$48.2M
– –
-6,710,429
Closed -$18.2M
MRNA icon
156
Moderna
MRNA
$22.1B
– –
-1,000,000
Closed -$27.9M
NPCE icon
157
Neuropace
NPCE
$522M
– –
-500,000
Closed -$5.57M
NVCR icon
158
NovoCure
NVCR
$1.97B
– –
-825,119
Closed -$14.7M
OSCR icon
159
Oscar Health
OSCR
$8.54B
– –
-11,649,591
Closed -$250M
PCVX icon
160
Vaxcyte
PCVX
$8.01B
– –
-225,000
Closed -$7.31M
RXST icon
161
RxSight
RXST
$233M
– –
-888,950
Closed -$11.6M
SLP icon
162
Simulations Plus
SLP
$371M
– –
-354,089
Closed -$6.18M
UHS icon
163
Universal Health Services
UHS
$9.64B
– –
-1,597
Closed -$289K
PACS icon
164
PACS Group
PACS
$7.45B
– –
-11,421
Closed -$148K
3 4 5 6
7

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GRQ
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PCM
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VA
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QC
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IC
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NW
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AAF
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Deerfield Management's Q3 2025 Portfolio in Review

As of Q3 2025, Deerfield Management held 171 positions worth $6.55B, up 19% from $5.51B the previous quarter. Its ten largest holdings account for 52% of the portfolio.

Deerfield Management's Q3 2025 filing shows 48 new, 43 increased, 20 reduced and 19 closed positions. Its largest new stake was Bristol-Myers Squibb: 2,337,771 shares worth $105M. The largest sale was Oscar Health, an estimated $250M.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 89% a quarter earlier, followed by Real Estate and Financials.

  • Deerfield Management's largest Q3 2025 buy was Bristol-Myers Squibb: 2,337,771 shares worth $105M.
  • Deerfield Management added most to Centene in Q3 2025, an estimated $177M increase.
  • Deerfield Management's biggest Q3 2025 reduction was Indivior Pharmaceuticals, cutting an estimated $74.9M.
  • Deerfield Management fully exited Oscar Health in Q3 2025, selling an estimated $250M.
  • Deerfield Management's ten largest holdings make up 52% of its $6.55B portfolio in Q3 2025.
  • Deerfield Management opened 48 new positions and closed 19 in Q3 2025.
  • Deerfield Management's portfolio value rose 19% quarter-over-quarter to $6.55B.

Based on Deerfield Management's 13F filing for Q3 2025, filed 14 Nov 2025.