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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
+9.69%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$5.51B
AUM Growth
+$445M
Cap. Flow
-$338M
Cap. Flow %
-6.13%
Top 10 Hldgs %
54.24%
Holding
167
New
43
Increased
28
Reduced
13
Closed
43

Top Buys

Rank Stock Value
1
UTHR icon
United Therapeutics
UTHR
+$79.3M
2
MRK icon
Merck
MRK
+$68.2M
3
VERA icon
Vera Therapeutics
VERA
+$51.7M
4
LEGN icon
Legend Biotech
LEGN
+$39.5M
5
CNC icon
Centene
CNC
+$30.1M

Sector Composition

Rank Sector Weight
1 Healthcare 89.05%
2 Real Estate 0.41%
3 Financials 0%
4 Industrials 0%
5 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
RZLT icon
151
Rezolute
RZLT
$444M
-19,223
Closed -$55.7K
TALK icon
152
Talkspace
TALK
$873M
-13,446
Closed -$34.4K
VIR icon
153
Vir Biotechnology
VIR
$1.59B
-15,728
Closed -$102K
WOOF icon
154
Petco
WOOF
$760M
-35,446
Closed -$108K
XPOF icon
155
Xponential Fitness
XPOF
$279M
-23,097
Closed -$192K
ZVRA icon
156
Zevra Therapeutics
ZVRA
$755M
-10,849
Closed -$81.3K
CON
157
Concentra Group Holdings
CON
$4.04B
-650,000
Closed -$14.1M
MTSR
158
DELISTED
Metsera Inc
MTSR
-500,000
Closed -$13.6M
CMRX
159
DELISTED
Chimerix, Inc.
CMRX
-3,771,342
Closed -$32.1M

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Deerfield Management's Q2 2025 Portfolio in Review

As of Q2 2025, Deerfield Management held 167 positions worth $5.51B, up 8.8% from $5.06B the previous quarter. Its ten largest holdings account for 54% of the portfolio.

Deerfield Management withdrew a net $338M in Q2 2025, closing 43 positions and reducing 13 holdings. Its most notable exit was Dynavax Technologies, an estimated $67.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 89% of assets, up from 87% a quarter earlier, followed by Real Estate and Financials.

Against the trend, Deerfield Management opened a new position in Merck worth $67.9M.

  • Deerfield Management's largest Q2 2025 buy was Merck: 857,724 shares worth $67.9M.
  • Deerfield Management added most to United Therapeutics in Q2 2025, an estimated $79.3M increase.
  • Deerfield Management's biggest Q2 2025 reduction was Alignment Healthcare, cutting an estimated $68M.
  • Deerfield Management fully exited Dynavax Technologies in Q2 2025, selling an estimated $67.3M.
  • Deerfield Management's ten largest holdings make up 54% of its $5.51B portfolio in Q2 2025.
  • Deerfield Management opened 43 new positions and closed 43 in Q2 2025.
  • Deerfield Management's portfolio value rose 8.8% quarter-over-quarter to $5.51B.

Based on Deerfield Management's 13F filing for Q2 2025, filed 14 Aug 2025.