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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
-5.44%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$5.06B
AUM Growth
-$215M
Cap. Flow
-$288M
Cap. Flow %
-5.68%
Top 10 Hldgs %
52.55%
Holding
152
New
45
Increased
20
Reduced
17
Closed
29

Top Buys

Rank Stock Value
1
UTHR icon
United Therapeutics
UTHR
+$94.3M
2
PFE icon
Pfizer
PFE
+$87.6M
3
NBIX icon
Neurocrine Biosciences
NBIX
+$79.4M
4
PRAX icon
Praxis Precision Medicines
PRAX
+$38.7M
5
INSM icon
Insmed
INSM
+$35M

Top Sells

Rank Stock Value
1
WAY
Waystar Holding Corp
WAY
+$121M
2
ACH
Accendra Health
ACH
+$64.2M
3
ALHC icon
Alignment Healthcare
ALHC
+$40.8M
4
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$38.8M
5
BCAX
Bicara Therapeutics
BCAX
+$31.3M

Sector Composition

Rank Sector Weight
1 Healthcare 87.22%
2 Real Estate 0.01%
3 Technology 0.01%
4 Consumer Discretionary 0.01%
5 Utilities 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GNW icon
126
Genworth Financial
GNW
$3.86B
– –
-11,307
Closed -$79K
HBI
127
DELISTED
Hanesbrands
HBI
– –
-10,619
Closed -$86.4K
HNST icon
128
The Honest Company
HNST
$412M
– –
-20,171
Closed -$140K
HTLD icon
129
Heartland Express
HTLD
$1.01B
– –
-11,547
Closed -$130K
IRTC icon
130
iRhythm Holdings
IRTC
$4.02B
– –
-156,012
Closed -$14.1M
NKTX icon
131
Nkarta
NKTX
$152M
– –
-2,155,000
Closed -$5.37M
NUS icon
132
Nu Skin
NUS
$257M
– –
-10,194
Closed -$70.2K
ACH
133
Accendra Health
ACH
$254M
– –
-4,911,979
Closed -$64.2M
OSUR icon
134
OraSure Technologies
OSUR
$273M
– –
-20,898
Closed -$75.4K
RXRX icon
135
Recursion Pharmaceuticals
RXRX
$1.58B
– –
-2,315,000
Closed -$15.6M
THRD
136
DELISTED
Third Harmonic Bio
THRD
– –
-1,019,700
Closed -$10.5M
UIS icon
137
Unisys
UIS
$252M
– –
-15,627
Closed -$98.9K
VTYX
138
DELISTED
Ventyx Biosciences
VTYX
– –
-534,737
Closed -$1.17M
WAY
139
Waystar Holding Corp
WAY
$4.7B
– –
-3,295,260
Closed -$121M
BCAX
140
Bicara Therapeutics
BCAX
$1.7B
– –
-1,795,174
Closed -$31.3M
SEPN
141
Septerna Inc
SEPN
$1.51B
– –
-861,814
Closed -$19.7M
EQC
142
DELISTED
Equity Commonwealth
EQC
– –
-43,258
Closed -$76.6K
ACCD
143
DELISTED
Accolade Inc
ACCD
– –
-3,475,000
Closed -$11.9M
ENLC
144
DELISTED
ENLINK MIDSTREAM, LLC
ENLC
– –
-10,257
Closed -$145K
OMIC
145
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
– –
-166,162
Closed -$3.23M
2 3 4 5
6

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Deerfield Management's Q1 2025 Portfolio in Review

As of Q1 2025, Deerfield Management held 152 positions worth $5.06B, down 4.1% from $5.28B the previous quarter. Its ten largest holdings account for 53% of the portfolio.

Deerfield Management withdrew a net $288M in Q1 2025, closing 29 positions and reducing 17 holdings. Its most notable exit was Waystar Holding Corp, an estimated $121M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, down from 88% a quarter earlier, followed by Real Estate and Technology.

Against the trend, Deerfield Management opened a new position in United Therapeutics worth $84.8M.

  • Deerfield Management's largest Q1 2025 buy was United Therapeutics: 275,226 shares worth $84.8M.
  • Deerfield Management added most to Neurocrine Biosciences in Q1 2025, an estimated $79.4M increase.
  • Deerfield Management's biggest Q1 2025 reduction was Alignment Healthcare, cutting an estimated $40.8M.
  • Deerfield Management fully exited Waystar Holding Corp in Q1 2025, selling an estimated $121M.
  • Deerfield Management's ten largest holdings make up 53% of its $5.06B portfolio in Q1 2025.
  • Deerfield Management opened 45 new positions and closed 29 in Q1 2025.
  • Deerfield Management's portfolio value fell 4.1% quarter-over-quarter to $5.06B.

Based on Deerfield Management's 13F filing for Q1 2025, filed 15 May 2025.