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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
+19.63%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$6.55B
AUM Growth
+$1.04B
Cap. Flow
+$118M
Cap. Flow %
1.81%
Top 10 Hldgs %
51.69%
Holding
171
New
48
Increased
43
Reduced
20
Closed
19

Top Buys

Rank Stock Value
1
CNC icon
Centene
CNC
+$177M
2
BMY icon
Bristol-Myers Squibb
BMY
+$109M
3
IONS icon
Ionis Pharmaceuticals
IONS
+$96.7M
4
INSP icon
Inspire Medical Systems
INSP
+$91.9M
5
COGT icon
Cogent Biosciences
COGT
+$76M

Top Sells

Rank Stock Value
1
OSCR icon
Oscar Health
OSCR
+$250M
2
INDV icon
Indivior Pharmaceuticals
INDV
+$74.9M
3
BAX icon
Baxter International
BAX
+$47.7M
4
IDYA icon
IDEAYA Biosciences
IDYA
+$42.6M
5
UTHR icon
United Therapeutics
UTHR
+$38.6M

Sector Composition

Rank Sector Weight
1 Healthcare 91.55%
2 Real Estate 0.38%
3 Financials 0.07%
4 Consumer Staples 0.07%
5 Consumer Discretionary 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PEN icon
101
Penumbra
PEN
$12.6B
$1.62M 0.02%
+6,411
New +$1.62M
NAMSW icon
102
NewAmsterdam Pharma Warrant
NAMSW
$87.4M
$1.59M 0.02%
92,787
– –
DXCM icon
103
DexCom
DXCM
$28.3B
$1.5M 0.02%
+22,287
New +$1.76M
TMDX icon
104
Transmedics
TMDX
$2.57B
$1.43M 0.02%
+12,752
New +$1.49M
AVNS icon
105
Avanos Medical
AVNS
$1.17B
$1.42M 0.02%
+122,899
New +$1.44M
PODD icon
106
Insulet
PODD
$11.4B
$1.38M 0.02%
+4,480
New +$1.4M
PHGE icon
107
BiomX
PHGE
$2.13M
$1.31M 0.02%
131,269
– –
ITGR icon
108
Integer Holdings
ITGR
$3.38B
$1.29M 0.02%
+12,528
New +$1.36M
DHR icon
109
Danaher
DHR
$138B
$1.27M 0.02%
6,421
+6,253
+3,722% +$1.24M
ZTS icon
110
Zoetis
ZTS
$32.2B
$1.25M 0.02%
8,554
+7,244
+553% +$1.09M
BRBR icon
111
BellRing Brands
BRBR
$1.52B
$1.24M 0.02%
+34,232
New +$1.55M
ELUT icon
112
Elutia
ELUT
$42.5M
$1.22M 0.02%
+1,371,603
New +$2.54M
AZTA icon
113
Azenta
AZTA
$1.27B
$1.18M 0.02%
+41,004
New +$1.27M
TECH icon
114
Bio-Techne
TECH
$11.2B
$1.17M 0.02%
+20,979
New +$1.12M
XERS icon
115
Xeris Biopharma Holdings
XERS
$1.42B
$984K 0.02%
120,900
+98,326
+436% +$653K
BAX icon
116
Baxter International
BAX
$12.1B
$973K 0.01%
42,744
-1,880,356
-98% -$47.7M
MOH icon
117
Molina Healthcare
MOH
$10.4B
$966K 0.01%
+5,047
New +$929K
ATEC icon
118
Alphatec Holdings
ATEC
$1.33B
$949K 0.01%
65,262
+48,179
+282% +$671K
ADPT icon
119
Adaptive Biotechnologies
ADPT
$3.61B
$903K 0.01%
+60,328
New +$735K
SYK icon
120
Stryker
SYK
$129B
$735K 0.01%
+1,988
New +$768K
MDXG icon
121
MiMedx Group
MDXG
$635M
$732K 0.01%
104,870
+65,519
+166% +$455K
TWST icon
122
Twist Bioscience
TWST
$5.39B
$670K 0.01%
23,827
– –
HQY icon
123
HealthEquity
HQY
$8.28B
$669K 0.01%
+7,060
New +$664K
STE icon
124
Steris
STE
$21.3B
$638K 0.01%
+2,578
New +$617K
GMED icon
125
Globus Medical
GMED
$10.6B
$636K 0.01%
+11,106
New +$640K
3 4
5
6 7

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Deerfield Management's Q3 2025 Portfolio in Review

As of Q3 2025, Deerfield Management held 171 positions worth $6.55B, up 19% from $5.51B the previous quarter. Its ten largest holdings account for 52% of the portfolio.

Deerfield Management's Q3 2025 filing shows 48 new, 43 increased, 20 reduced and 19 closed positions. Its largest new stake was Bristol-Myers Squibb: 2,337,771 shares worth $105M. The largest sale was Oscar Health, an estimated $250M.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 89% a quarter earlier, followed by Real Estate and Financials.

  • Deerfield Management's largest Q3 2025 buy was Bristol-Myers Squibb: 2,337,771 shares worth $105M.
  • Deerfield Management added most to Centene in Q3 2025, an estimated $177M increase.
  • Deerfield Management's biggest Q3 2025 reduction was Indivior Pharmaceuticals, cutting an estimated $74.9M.
  • Deerfield Management fully exited Oscar Health in Q3 2025, selling an estimated $250M.
  • Deerfield Management's ten largest holdings make up 52% of its $6.55B portfolio in Q3 2025.
  • Deerfield Management opened 48 new positions and closed 19 in Q3 2025.
  • Deerfield Management's portfolio value rose 19% quarter-over-quarter to $6.55B.

Based on Deerfield Management's 13F filing for Q3 2025, filed 14 Nov 2025.