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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
-6.2%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$4.77B
AUM Growth
-$356M
Cap. Flow
-$1.35B
Cap. Flow %
-28.26%
Top 10 Hldgs %
39.93%
Holding
155
New
23
Increased
16
Reduced
21
Closed
28

Top Buys

Rank Stock Value
1
DCPH
Deciphera Pharmaceuticals, Inc. Common Stock
DCPH
+$89.6M
2
AHCO icon
AdaptHealth
AHCO
+$49.8M
3
ESPR
Esperion Therapeutics
ESPR
+$40M
4
XLO icon
Xilio Therapeutics
XLO
+$36.7M
5
FIGS icon
FIGS
FIGS
+$27.3M

Top Sells

Rank Stock Value
1
BDSI
BioDelivery Sciences International, Inc.
BDSI
+$30.8M
2
MOH icon
Molina Healthcare
MOH
+$28.8M
3
CYTK icon
Cytokinetics
CYTK
+$28.1M
4
XLRN
Acceleron Pharma
XLRN
+$25M
5
FATE icon
Fate Therapeutics
FATE
+$21.5M

Sector Composition

Rank Sector Weight
1 Healthcare 62.96%
2 Financials 1.4%
3 Consumer Discretionary 0.48%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
HYPR icon
76
Hyperfine
HYPR
$95.3M
$7.25M 0.15%
+1,000,000
New +$7.92M
PKBO
77
DELISTED
Peak Bio, Inc. Common Stock
PKBO
$7.06M 0.15%
725,000
– –
DH icon
78
Definitive Healthcare
DH
$71.1M
$6.83M 0.14%
250,000
– –
ANNX icon
79
Annexon
ANNX
$841M
$6.71M 0.14%
583,913
– –
AMWL icon
80
American Well
AMWL
$185M
$5.99M 0.13%
49,556
– –
BCAB icon
81
BioAtla
BCAB
$5.64M
$5.67M 0.12%
5,780
-3,506
-38% -$4.48M
OHPA
82
DELISTED
Orion Acquisition Corp. Class A common stock
OHPA
$4.89M 0.1%
500,000
– –
DCTH icon
83
Delcath Systems
DCTH
$412M
$3.88M 0.08%
500,000
– –
PYXS icon
84
Pyxis Oncology
PYXS
$184M
$3.42M 0.07%
+311,754
New +$3.57M
ROIVW
85
DELISTED
Roivant Sciences Ltd. Warrant
ROIVW
$2.05M 0.04%
+1,000,000
New +$1.53M
GKOS icon
86
CALL
Glaukos
GKOS
$8.92B
$2.01M 0.04%
+45,200
New +$2.09M
CABA icon
87
Cabaletta Bio
CABA
$444M
$1.76M 0.04%
464,252
– –
WVE icon
88
Wave Life Sciences
WVE
$1.14B
$1.74M 0.04%
552,690
-2,661,650
-83% -$11.1M
MDVL
89
DELISTED
MedAvail Holdings, Inc. Common Stock
MDVL
$1.6M 0.03%
22,851
– –
CMAXW
90
DELISTED
CareMax, Inc. Warrant
CMAXW
$941K 0.02%
672,000
– –
BFLY.WS
91
DELISTED
Butterfly Network Inc Warrants
BFLY.WS
$931K 0.02%
733,333
– –
TOIIW
92
The Oncology Institute Warrant
TOIIW
$863K 0.02%
1,250,000
– –
QSIAW
93
DELISTED
Quantum-Si Inc Warrant
QSIAW
$600K 0.01%
333,333
– –
SLGCW
94
DELISTED
SomaLogic, Inc. Warrant
SLGCW
$401K 0.01%
120,000
– –
NUVB.WS
95
DELISTED
Nuvation Bio Inc Warrants
NUVB.WS
$315K 0.01%
166,666
– –
PKBOW
96
DELISTED
Peak Bio, Inc. Warrant
PKBOW
$279K 0.01%
362,500
– –
SNRHW
97
DELISTED
Senior Connect Acquisition Corp. I Warrant
SNRHW
$263K 0.01%
500,000
– –
EUCRW
98
DELISTED
Eucrates Biomedical Acquisition Corp. Warrant
EUCRW
$193K ﹤0.01%
+333,333
New +$245K
SRZNW icon
99
Surrozen Inc Warrant
SRZNW
$75.6K
$192K ﹤0.01%
166,666
– –
TLSIW icon
100
TriSalus Life Sciences Warrant
TLSIW
$25.5M
$174K ﹤0.01%
333,333
– –
2 3
4
5 6

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GRQ
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PCM
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VA
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QC
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IC
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NW
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AAF
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Deerfield Management's Q4 2021 Portfolio in Review

As of Q4 2021, Deerfield Management held 155 positions worth $4.77B, down 7% from $5.12B the previous quarter. Its ten largest holdings account for 40% of the portfolio.

Deerfield Management withdrew a net $1.35B in Q4 2021, closing 28 positions and reducing 21 holdings. Its most notable exit was Acceleron Pharma, an estimated $25M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 63% of assets, down from 66% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Deerfield Management opened a new position in Esperion Therapeutics worth $25M.

  • Deerfield Management's largest Q4 2021 buy was Esperion Therapeutics: 5,000,000 shares worth $25M.
  • Deerfield Management added most to Deciphera Pharmaceuticals, Inc. Common Stock in Q4 2021, an estimated $89.6M increase.
  • Deerfield Management's biggest Q4 2021 reduction was BioDelivery Sciences International, Inc., cutting an estimated $30.8M.
  • Deerfield Management fully exited Acceleron Pharma in Q4 2021, selling an estimated $25M.
  • Deerfield Management's ten largest holdings make up 40% of its $4.77B portfolio in Q4 2021.
  • Deerfield Management opened 23 new positions and closed 28 in Q4 2021.
  • Deerfield Management's portfolio value fell 7% quarter-over-quarter to $4.77B.

Based on Deerfield Management's 13F filing for Q4 2021, filed 14 Feb 2022.