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Deerfield Management Portfolio holdings

AUM $8.48B
1-Year Est. Return 99.04%
This Fund
S&P 500
This Quarter Est. Return
-6.2%
1 Year Est. Return
+99.04%
3 Year Est. Return
+273.78%
5 Year Est. Return
+280.99%
10 Year Est. Return
+2,168.14%
AUM
$4.77B
AUM Growth
-$356M
Cap. Flow
-$1.35B
Cap. Flow %
-28.26%
Top 10 Hldgs %
39.93%
Holding
155
New
23
Increased
16
Reduced
21
Closed
28

Sector Composition

Rank Sector Weight
1 Healthcare 62.96%
2 Financials 1.4%
3 Consumer Discretionary 0.48%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
XLO icon
26
Xilio Therapeutics
XLO
$58.4M
$33.7M 0.71%
+153,862
New +$36.7M
AERI
27
DELISTED
Aerie Pharmaceuticals
AERI
$33M 0.69%
4,695,020
+1,718,000
+58% +$18M
TOI icon
28
The Oncology Institute
TOI
$535M
$32.1M 0.67%
3,296,107
-1,703,893
-34% -$15.1M
NUVB icon
29
Nuvation Bio
NUVB
$2.02B
$30.4M 0.64%
3,577,233
SWTX
30
DELISTED
SpringWorks Therapeutics
SWTX
$28M 0.59%
452,000
-58,673
-11% -$3.88M
ESPR
31
DELISTED
Esperion Therapeutics
ESPR
$25M 0.52%
+5,000,000
New +$40M
BCRX icon
32
BioCryst Pharmaceuticals
BCRX
$2.36B
$23.4M 0.49%
1,686,140
+1,451,497
+619% +$19.2M
VIVO
33
DELISTED
Meridian Bioscience Inc
VIVO
$23M 0.48%
1,125,083
-938,000
-45% -$18M
FIGS icon
34
FIGS
FIGS
$1.72B
$22.9M 0.48%
+829,707
New +$27.3M
PHVS icon
35
Pharvaris
PHVS
$2.44B
$22.8M 0.48%
1,581,331
-27,140
-2% -$424K
RVMD icon
36
Revolution Medicines
RVMD
$39.6B
$22.4M 0.47%
891,587
-674,125
-43% -$19M
BKD icon
37
Brookdale Senior Living
BKD
$3.58B
$22.1M 0.46%
4,274,808
-977,992
-19% -$6.1M
ALEC icon
38
Alector
ALEC
$167M
$21.8M 0.46%
1,055,192
BLU
39
DELISTED
BELLUS Health Inc.
BLU
$19.7M 0.41%
+2,449,000
New +$16.3M
PROF
40
Profound Medical
PROF
$249M
$19.2M 0.4%
1,713,797
+416,000
+32% +$5.2M
RYTM icon
41
Rhythm Pharmaceuticals
RYTM
$7.31B
$18.6M 0.39%
1,867,467
-122,158
-6% -$1.37M
OM icon
42
Outset Medical
OM
$77.9M
$18.5M 0.39%
26,708
NVRO
43
DELISTED
NEVRO CORP.
NVRO
$17.5M 0.37%
+216,000
New +$21.6M
KNTE
44
DELISTED
Kinnate Biopharma Inc. Common Stock
KNTE
$17.5M 0.37%
985,568
-42,940
-4% -$906K
BBIO icon
45
CALL
BridgeBio Pharma
BBIO
$15.9B
$16.7M 0.35%
+1,000,000
New +$42.3M
ONCR
46
DELISTED
Oncorus, Inc.
ONCR
$16.6M 0.35%
3,148,977
TERN
47
DELISTED
Terns Pharmaceuticals
TERN
$16.6M 0.35%
2,345,959
APLS
48
DELISTED
Apellis Pharmaceuticals
APLS
$16.2M 0.34%
+343,213
New +$13.5M
INZY
49
DELISTED
Inozyme Pharma
INZY
$16M 0.34%
2,344,786
DALS
50
DELISTED
DA32 Life Science Tech Acquisition Corp. Class A Common Stock
DALS
$15.7M 0.33%
1,600,000

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Deerfield Management's Q4 2021 Portfolio in Review

As of Q4 2021, Deerfield Management held 155 positions worth $4.77B, down 7% from $5.12B the previous quarter. Its ten largest holdings account for 40% of the portfolio.

Deerfield Management withdrew a net $1.35B in Q4 2021, closing 28 positions and reducing 21 holdings. Its most notable exit was Acceleron Pharma, an estimated $25M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 63% of assets, down from 66% a quarter earlier, followed by Financials and Consumer Discretionary.

Against the trend, Deerfield Management opened a new position in Esperion Therapeutics worth $25M.

  • Deerfield Management's largest Q4 2021 buy was Esperion Therapeutics: 5,000,000 shares worth $25M.
  • Deerfield Management added most to Deciphera Pharmaceuticals, Inc. Common Stock in Q4 2021, an estimated $89.6M increase.
  • Deerfield Management's biggest Q4 2021 reduction was BioDelivery Sciences International, Inc., cutting an estimated $30.8M.
  • Deerfield Management fully exited Acceleron Pharma in Q4 2021, selling an estimated $25M.
  • Deerfield Management's ten largest holdings make up 40% of its $4.77B portfolio in Q4 2021.
  • Deerfield Management opened 23 new positions and closed 28 in Q4 2021.
  • Deerfield Management's portfolio value fell 7% quarter-over-quarter to $4.77B.

Based on Deerfield Management's 13F filing for Q4 2021, filed 14 Feb 2022.