D.E. Shaw & Co Portfolio holdings
D. E. Shaw & Co., L.P., founded in 1988 by David E. Shaw, a former Columbia University computer science professor, is a New York City-based global investment management firm renowned for pioneering quantitative investing, managing over $70 billion in assets as of late 2024. Starting with $28 million from Paloma Partners and private investors, the firm employs sophisticated mathematical models and proprietary algorithms—initially developed by a team of scientists and programmers—to exploit market anomalies across public and private markets, including equities, fixed income, and alternatives. Headquartered above a Greenwich Village bookstore in its early days, it now boasts over 2,500 employees across offices in North America, Europe, and Asia, led by a seven-member Executive Committee since Shaw stepped back in 2001 to focus on D. E. Shaw Research. Despite setbacks like the 1998 Russia debt crisis and the 2008 financial downturn, the firm has maintained a reputation for analytical rigor, risk management, and innovation, balancing its computational roots with discretionary strategies.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Microsoft
MSFT
|
+$1.9B |
| 2 |
Broadcom
AVGO
|
+$1.07B |
| 3 |
NVIDIA
NVDA
|
+$908M |
| 4 |
Meta Platforms (Facebook)
META
|
+$861M |
| 5 |
Intuitive Surgical
ISRG
|
+$666M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
State Street SPDR S&P 500 ETF Trust
SPY
|
+$1.68B |
| 2 |
Apple
AAPL
|
+$1.31B |
| 3 |
State Street Financial Select Sector SPDR ETF
XLF
|
+$789M |
| 4 |
GE Aerospace
GE
|
+$653M |
| 5 |
Applovin
APP
|
+$634M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 19.25% |
| 2 | Consumer Discretionary | 7.51% |
| 3 | Financials | 7.11% |
| 4 | Healthcare | 6.95% |
| 5 | Industrials | 6.31% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
801
Pediatrix Medical
MD
$2.18B
| $33.9M | 0.02% |
2,021,337
+443,575
| +28% | +$6.65M |
|
802
Liquidia Corp
LQDA
$7.48B
| $33.8M | 0.02% |
1,487,901
+1,341,462
| +916% | +$29.1M |
|
803
PUT
Bristol-Myers Squibb
BMY
$133B
| $33.8M | 0.02% |
749,000
+150,500
| +25% | +$7.03M |
|
804
KraneShares CSI China Internet ETF
KWEB
$5.64B
| $33.8M | 0.02% |
803,482
-1,532,949
| -66% | -$57.5M |
|
805
Monster Beverage
MNST
$94.3B
| $33.7M | 0.02% |
500,654
-518,773
| -51% | -$32.4M |
|
806
Prestige Consumer Healthcare
PBH
$2.38B
| $33.6M | 0.02% |
538,025
+251,417
| +88% | +$17.5M |
|
807
UBS Group
UBS
$173B
| $33.6M | 0.02% |
818,817
+420,468
| +106% | +$16.3M |
|
808
CALL
Cameco
CCJ
$37.6B
| $33.5M | 0.02% |
399,900
+316,000
| +377% | +$24.5M |
|
809
PUT
Celsius Holdings
CELH
$7.47B
| $33.5M | 0.02% |
582,200
+20,700
| +4% | +$1.08M |
|
810
CALL
Vale
VALE
$64.1B
| $33.5M | 0.02% |
+3,081,500
| New | +$31.5M |
|
811
Repligen
RGEN
$7.96B
| $33.4M | 0.02% |
249,930
+244,298
| +4,338% | +$29.7M |
|
812
West Pharmaceutical
WST
$24B
| $33.4M | 0.02% |
127,146
-157,190
| -55% | -$38.2M |
|
813
CALL
Telus
TU
$14.9B
| $33.3M | 0.02% |
2,117,300
+992,300
| +88% | +$16.1M |
|
814
Acadia Pharmaceuticals
ACAD
$4.43B
| $33.3M | 0.02% |
1,561,161
-403,360
| -21% | -$9.54M |
|
815
PUT
Okta
OKTA
$24.7B
| $33.3M | 0.02% |
363,300
+187,700
| +107% | +$17.5M |
|
816
WisdomTree
WT
$2.96B
| $33.3M | 0.02% |
2,392,924
+1,795,580
| +301% | +$24M |
|
817
Apollo Global Management Series A
APO.PRA
$1.76B
| $33.1M | 0.02% |
470,000
-50,000
| -10% | -$3.72M |
|
818
CALL
Chipotle Mexican Grill
CMG
$47.2B
| $33M | 0.02% |
841,700
+15,100
| +2% | +$680K |
|
819
Myriad Genetics
MYGN
$270M
| $33M | 0.02% |
4,559,136
+47,639
| +1% | +$283K |
|
820
Goldman Sachs
GS
$300B
| $32.9M | 0.02% |
41,311
+17,054
| +70% | +$12.6M |
|
821
Carter's
CRI
$1.42B
| $32.9M | 0.02% |
1,164,649
-539,322
| -32% | -$15.5M |
|
822
Burlington
BURL
$23.2B
| $32.6M | 0.02% |
128,069
+23,222
| +22% | +$6.31M |
|
|
BNY
823
Bank of New York Mellon
BNY
$106B
| $32.5M | 0.02% |
297,869
-57,987
| -16% | -$5.91M |
|
824
MarketAxess Holdings
MKTX
$5.71B
| $32.3M | 0.02% |
185,618
+16,720
| +10% | +$3.27M |
|
825
CALL
Duolingo
DUOL
$6.28B
| $32.2M | 0.02% |
100,000
+34,100
| +52% | +$11.4M |
|
Similar funds
D.E. Shaw & Co's Q3 2025 Portfolio in Review
As of Q3 2025, D.E. Shaw & Co held 5,023 positions worth $177B, up 26% from $141B the previous quarter. Its ten largest holdings account for 13% of the portfolio.
D.E. Shaw & Co deployed $15.2B of net new capital in Q3 2025, opening 714 new positions and adding to 1,743 existing holdings. Its largest new stake was iShares iBoxx $ Investment Grade Corporate Bond ETF: 3,319,000 shares worth $370M.
By sector, the portfolio is most concentrated in Technology at 19% of assets, up from 16% a quarter earlier, followed by Consumer Discretionary and Financials.
On the sell side, the largest reduction was State Street SPDR S&P 500 ETF Trust, an estimated $1.68B trimmed.
- D.E. Shaw & Co's largest Q3 2025 buy was iShares iBoxx $ Investment Grade Corporate Bond ETF: 3,319,000 shares worth $370M.
- D.E. Shaw & Co added most to Microsoft in Q3 2025, an estimated $1.9B increase.
- D.E. Shaw & Co's biggest Q3 2025 reduction was State Street SPDR S&P 500 ETF Trust, cutting an estimated $1.68B.
- D.E. Shaw & Co fully exited Hess in Q3 2025, selling an estimated $527M.
- D.E. Shaw & Co's ten largest holdings make up 13% of its $177B portfolio in Q3 2025.
- D.E. Shaw & Co opened 714 new positions and closed 514 in Q3 2025.
- D.E. Shaw & Co's portfolio value rose 26% quarter-over-quarter to $177B.
Based on D.E. Shaw & Co's 13F filing for Q3 2025, filed 14 Nov 2025.