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Cubist Systematic Strategies Portfolio holdings

AUM $21B
1-Year Est. Return 21.48%
This Fund
S&P 500
This Quarter Est. Return
+13.25%
1 Year Est. Return
+21.48%
3 Year Est. Return
+78.34%
5 Year Est. Return
+110.56%
10 Year Est. Return
+239.02%
AUM
$21B
AUM Growth
-$759M
Cap. Flow
-$2.65B
Cap. Flow %
-12.62%
Top 10 Hldgs %
5.95%
Holding
3,694
New
805
Increased
903
Reduced
1,135
Closed
746

Top Buys

Rank Stock Value
1
KDP icon
Keurig Dr Pepper
KDP
+$74.2M
2
BSX icon
Boston Scientific
BSX
+$46.7M
3
ADSK icon
Autodesk
ADSK
+$46.4M
4
KEY icon
KeyCorp
KEY
+$43.9M
5
TEL icon
TE Connectivity
TEL
+$40.8M

Top Sells

Rank Stock Value
1
ADBE icon
Adobe
ADBE
+$111M
2
SOFI icon
SoFi Technologies
SOFI
+$101M
3
MA icon
Mastercard
MA
+$98.7M
4
ABBV icon
AbbVie
ABBV
+$97.4M
5
APH icon
Amphenol
APH
+$73.6M

Sector Composition

Rank Sector Weight
1 Technology 6.05%
2 Financials 5.25%
3 Industrials 4.83%
4 Healthcare 3.93%
5 Consumer Discretionary 3.52%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ENTX icon
2926
Entera Bio
ENTX
$161M
$8.97K ﹤0.01%
4,673
+3,858
+473% +$7.38K
IPW icon
2927
iPower
IPW
$1.19M
$8.79K ﹤0.01%
+71
New +$10.1K
ITOC
2928
iTonic Holdings
ITOC
$4.42M
$8.45K ﹤0.01%
+10,852
New +$77.7K
PSTV icon
2929
Plus Therapeutics
PSTV
$25.9M
$7.97K ﹤0.01%
466
+57
+14% +$700
PRPL icon
2930
Purple Innovation
PRPL
$35.7M
$7.5K ﹤0.01%
321
-2,949
-90% -$69K
SERA icon
2931
Sera Prognostics
SERA
$79.5M
$7.12K ﹤0.01%
+2,328
New +$6.63K
HAIN icon
2932
Hain Celestial
HAIN
$44.8M
$7.02K ﹤0.01%
4,444
-115,817
-96% -$197K
CYCU
2933
Cycurion Inc
CYCU
$3.43M
$6.96K ﹤0.01%
+593
New +$5.58K
BMEA icon
2934
Biomea Fusion
BMEA
$90.4M
$6.8K ﹤0.01%
3,369
+2,521
+297% +$4.62K
TNYA icon
2935
Tenaya Therapeutics
TNYA
$164M
$6.67K ﹤0.01%
4,115
-191,983
-98% -$193K
OTLK icon
2936
Outlook Therapeutics
OTLK
$169M
$5.61K ﹤0.01%
5,295
+5,269
+20,265% +$9.11K
GPUS
2937
Hyperscale Data Inc
GPUS
$55M
$5.35K ﹤0.01%
+11,767
New +$8.39K
MXCT icon
2938
MaxCyte
MXCT
$112M
$5.09K ﹤0.01%
+3,225
New +$5.61K
ABVEW
2939
DELISTED
Above Food Ingredients Inc Warrants
ABVEW
$4.62K ﹤0.01%
19,264
– –
LI icon
2940
CALL
Li Auto
LI
$13.8B
$2.53K ﹤0.01%
100
– –
LIMNW
2941
Liminatus Pharma Warrants
LIMNW
$318K
$2.33K ﹤0.01%
15,778
– –
SLNH icon
2942
Soluna Holdings
SLNH
$192M
$2.09K ﹤0.01%
+891
New +$752
BNZIW icon
2943
Banzai International Warrant
BNZIW
$126K
$596 ﹤0.01%
22,319
– –
SCWO icon
2944
374Water
SCWO
$38.8M
$286 ﹤0.01%
100
-324
-76% -$887
CVGI icon
2945
Commercial Vehicle Group
CVGI
$152M
$142 ﹤0.01%
+84
New +$154
STRO icon
2946
Sutro Biopharma
STRO
$393M
$9 ﹤0.01%
1
-607
-100% -$5.17K
ATNM icon
2947
Actinium Pharmaceuticals
ATNM
$27.2M
$2 ﹤0.01%
1
-1,926
-100% -$3.14K
NAUT icon
2948
Nautilus Biotechnolgy
NAUT
$152M
$1 ﹤0.01%
1
-62,346
-100% -$45.8K
ABBV icon
2949
AbbVie
ABBV
$465B
– –
-478,201
Closed -$97.4M
ABG icon
2950
Asbury Automotive
ABG
$4.49B
– –
-1,618
Closed -$386K
116 117
118
119 120

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ECM
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JFL
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BAM
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SF
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WIM
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AIM
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SIG
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Cubist Systematic Strategies's Q3 2025 Portfolio in Review

As of Q3 2025, Cubist Systematic Strategies held 3,694 positions worth $21B, down 3.5% from $21.8B the previous quarter. Its ten largest holdings account for 6% of the portfolio.

Cubist Systematic Strategies withdrew a net $2.65B in Q3 2025, closing 746 positions and reducing 1,135 holdings. Its most notable exit was Adobe, an estimated $111M position sold in full.

By sector, the portfolio is most concentrated in Technology at 6% of assets, down from 7.6% a quarter earlier, followed by Financials and Industrials.

Against the trend, Cubist Systematic Strategies opened a new position in Keurig Dr Pepper worth $60.4M.

  • Cubist Systematic Strategies's largest Q3 2025 buy was Keurig Dr Pepper: 2,366,205 shares worth $60.4M.
  • Cubist Systematic Strategies added most to Boston Scientific in Q3 2025, an estimated $46.7M increase.
  • Cubist Systematic Strategies's biggest Q3 2025 reduction was McDonald's, cutting an estimated $62.3M.
  • Cubist Systematic Strategies fully exited Adobe in Q3 2025, selling an estimated $111M.
  • Cubist Systematic Strategies's ten largest holdings make up 6% of its $21B portfolio in Q3 2025.
  • Cubist Systematic Strategies opened 805 new positions and closed 746 in Q3 2025.
  • Cubist Systematic Strategies's portfolio value fell 3.5% quarter-over-quarter to $21B.

Based on Cubist Systematic Strategies's 13F filing for Q3 2025, filed 14 Nov 2025.