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Bellevue Group Portfolio holdings
AUM
$4.2B
1-Year Est. Return
54.85%
This Fund
S&P 500
This Quarter
Est. Return
+23.65%
1 Year Est. Return
+54.85%
3 Year Est. Return
+140.3%
5 Year Est. Return
+171.01%
10 Year Est. Return
+915.55%
AUM
$5.28B
AUM Growth
+$464M
(+9.6%)
Cap. Flow
-$292M
Cap. Flow
% of AUM
-5.53%
Top 10 Holdings %
Top 10 Hldgs %
49.47%
Holding
185
New
37
Increased
47
Reduced
83
Closed
9
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Viridian Therapeutics
VRDN
|
+$120M |
| 2 |
FOLD
Amicus Therapeutics
FOLD
|
+$105M |
| 3 |
NUVL
Nuvalent
NUVL
|
+$102M |
| 4 |
Krystal Biotech
KRYS
|
+$86.1M |
| 5 |
Vertex Pharmaceuticals
VRTX
|
+$75.6M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Agios Pharmaceuticals
AGIO
|
+$149M |
| 2 |
Incyte
INCY
|
+$139M |
| 3 |
AKRO
Akero Therapeutics
AKRO
|
+$113M |
| 4 |
Ionis Pharmaceuticals
IONS
|
+$109M |
| 5 |
argenx
ARGX
|
+$72.3M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Healthcare | 99.71% |
| 2 | Technology | 0.1% |
| 3 | Consumer Discretionary | 0.05% |
| 4 | Financials | 0.03% |
| 5 | Communication Services | 0.02% |
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Bellevue Group's Q4 2025 Portfolio in Review
As of Q4 2025, Bellevue Group held 185 positions worth $5.28B, up 9.6% from $4.81B the previous quarter. Its ten largest holdings account for 49% of the portfolio.
Bellevue Group withdrew a net $292M in Q4 2025, closing 9 positions and reducing 83 holdings. Its most notable exit was Agios Pharmaceuticals, an estimated $149M position sold in full.
By sector, the portfolio is most concentrated in Healthcare at 100% of assets, down from 100% a quarter earlier, followed by Technology and Consumer Discretionary.
Against the trend, Bellevue Group opened a new position in Viridian Therapeutics worth $136M.
- Bellevue Group's largest Q4 2025 buy was Viridian Therapeutics: 4,358,527 shares worth $136M.
- Bellevue Group added most to Krystal Biotech in Q4 2025, an estimated $86.1M increase.
- Bellevue Group's biggest Q4 2025 reduction was Incyte, cutting an estimated $139M.
- Bellevue Group fully exited Agios Pharmaceuticals in Q4 2025, selling an estimated $149M.
- Bellevue Group's ten largest holdings make up 49% of its $5.28B portfolio in Q4 2025.
- Bellevue Group opened 37 new positions and closed 9 in Q4 2025.
- Bellevue Group's portfolio value rose 9.6% quarter-over-quarter to $5.28B.
Based on Bellevue Group's 13F filing for Q4 2025, filed 17 Feb 2026.