ACA

Avoro Capital Advisors Portfolio holdings

AUM $5.71B
1-Year Return 11.37%
This Quarter Return
+3.66%
1 Year Return
+11.37%
3 Year Return
+255.37%
5 Year Return
+558.9%
10 Year Return
+18,722.72%
AUM
$7.51B
AUM Growth
-$1.07B
Cap. Flow
-$924M
Cap. Flow %
-12.31%
Top 10 Hldgs %
65.31%
Holding
49
New
3
Increased
11
Reduced
9
Closed
8

Top Buys

1
ITCI
Intra-Cellular Therapies Inc.
ITCI
$36M
2
ASND icon
Ascendis Pharma
ASND
$31.4M
3
MDGL icon
Madrigal Pharmaceuticals
MDGL
$31.1M
4
RNA icon
Avidity Biosciences
RNA
$27.8M
5
MRUS icon
Merus
MRUS
$27.6M

Top Sells

1
VKTX icon
Viking Therapeutics
VKTX
$294M
2
ALPN
Alpine Immune Sciences, Inc. Common Stock
ALPN
$229M
3
SRPT icon
Sarepta Therapeutics
SRPT
$212M
4
XBI icon
SPDR S&P Biotech ETF
XBI
$117M
5
MGNX icon
MacroGenics
MGNX
$90.5M

Sector Composition

1 Healthcare 96.25%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
OCUL icon
26
Ocular Therapeutix
OCUL
$2.37B
$55.1M 0.73%
8,060,000
+911,064
+13% +$6.23M
MNKD icon
27
MannKind Corp
MNKD
$1.7B
$45.7M 0.61%
8,759,524
-240,476
-3% -$1.26M
PCVX icon
28
Vaxcyte
PCVX
$4.29B
$43.4M 0.58%
575,000
– –
SYRE icon
29
Spyre Therapeutics
SYRE
$1.03B
$43.2M 0.58%
1,839,138
– –
AUTL
30
Autolus Therapeutics
AUTL
$389M
$43M 0.57%
12,345,678
– –
TSHA icon
31
Taysha Gene Therapies
TSHA
$917M
$41.8M 0.56%
18,650,000
– –
RARE icon
32
Ultragenyx Pharmaceutical
RARE
$3.07B
$34.1M 0.45%
830,000
– –
VRCA icon
33
Verrica Pharmaceuticals
VRCA
$48.2M
$29.2M 0.39%
400,000
– –
TRML icon
34
Tourmaline Bio
TRML
$687M
$28.6M 0.38%
2,222,222
– –
CGON icon
35
CG Oncology
CGON
$2.52B
$22.1M 0.29%
700,000
– –
GLUE icon
36
Monte Rosa Therapeutics
GLUE
$305M
$17M 0.23%
4,535,000
– –
BCYC
37
Bicycle Therapeutics
BCYC
$496M
$14.2M 0.19%
+700,000
New +$14.2M
WHWK
38
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$85.8M
$4.16M 0.06%
2,849,402
– –
DYN icon
39
Dyne Therapeutics
DYN
$2.02B
$4.08M 0.05%
+115,751
New +$4.08M
ADVM icon
40
Adverum Biotechnologies
ADVM
$73.9M
$2.86M 0.04%
416,666
– –
NGNE icon
41
Neurogene
NGNE
$285M
$802K 0.01%
+22,029
New +$802K
CRSP icon
42
CRISPR Therapeutics
CRSP
$4.99B
– –
-419,580
Closed -$28.6M
MGNX icon
43
MacroGenics
MGNX
$126M
– –
-6,150,000
Closed -$90.5M
RCKT icon
44
Rocket Pharmaceuticals
RCKT
$354M
– –
-1,260,900
Closed -$34M
ROIV icon
45
Roivant Sciences
ROIV
$8.82B
– –
-4,651,162
Closed -$49M
VKTX icon
46
Viking Therapeutics
VKTX
$3.03B
– –
-3,590,000
Closed -$294M
KYTX icon
47
Kyverna Therapeutics
KYTX
$170M
– –
-475,000
Closed -$11.8M
ALPN
48
DELISTED
Alpine Immune Sciences, Inc. Common Stock
ALPN
– –
-5,775,000
Closed -$229M
MRNS
49
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
– –
-4,140,607
Closed -$37.4M
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