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Avoro Capital Advisors Portfolio holdings

AUM $11.1B
1-Year Est. Return 207.82%
This Fund
S&P 500
This Quarter Est. Return
+29.18%
1 Year Est. Return
+207.82%
3 Year Est. Return
+512.05%
5 Year Est. Return
+1,035%
10 Year Est. Return
+45,230.58%
AUM
$11.1B
AUM Growth
+$971M
Cap. Flow
-$906M
Cap. Flow %
-8.14%
Top 10 Hldgs %
79.46%
Holding
34
New
2
Increased
12
Reduced
3
Closed
8

Top Buys

Rank Stock Value
1
CYTK icon
Cytokinetics
CYTK
+$120M
2
UTHR icon
United Therapeutics
UTHR
+$83.2M
3
DFTX
Definium Therapeutics
DFTX
+$54.1M
4
COAG
Hemab Therapeutics
COAG
+$53.1M
5
ARWR icon
Arrowhead Research
ARWR
+$48.4M

Top Sells

Rank Stock Value
1
APLS
Apellis Pharmaceuticals
APLS
+$492M
2
CNTA
Centessa Pharmaceuticals
CNTA
+$454M
3
TERN
Terns Pharmaceuticals
TERN
+$300M
4
SLNO
Soleno Therapeutics
SLNO
+$77M
5
ALKS icon
Alkermes
ALKS
+$42.4M

Sector Composition

Rank Sector Weight
1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LXEO icon
26
Lexeo Therapeutics
LXEO
$409M
$6.93M 0.06%
1,489,189
-385,811
-21% -$2.09M
ALKS icon
27
Alkermes
ALKS
$8.2B
– –
-1,200,000
Closed -$42.4M
APLS
28
DELISTED
Apellis Pharmaceuticals
APLS
– –
-12,222,222
Closed -$492M
CELC icon
29
CALL
Celcuity
CELC
$4.56B
– –
-200,000
Closed -$3.05M
CNTA
30
DELISTED
Centessa Pharmaceuticals
CNTA
– –
-11,430,455
Closed -$454M
MNKD icon
31
MannKind Corp
MNKD
$1.31B
– –
-2,200,000
Closed -$5.39M
SLNO
32
DELISTED
Soleno Therapeutics
SLNO
– –
-2,300,000
Closed -$77M
TERN
33
DELISTED
Terns Pharmaceuticals
TERN
– –
-5,695,000
Closed -$300M
UTHR icon
34
CALL
United Therapeutics
UTHR
$22.6B
– –
-380,000
Closed -$10.3M
1
2

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VNIM
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Avoro Capital Advisors's Q2 2026 Portfolio in Review

As of Q2 2026, Avoro Capital Advisors held 34 positions worth $11.1B, up 9.6% from $10.2B the previous quarter. Its ten largest holdings account for 79% of the portfolio.

Avoro Capital Advisors withdrew a net $906M in Q2 2026, closing 8 positions and reducing 3 holdings. Its most notable exit was Apellis Pharmaceuticals, an estimated $492M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier.

Against the trend, Avoro Capital Advisors opened a new position in Hemab Therapeutics worth $70.7M.

  • Avoro Capital Advisors's largest Q2 2026 buy was Hemab Therapeutics: 1,925,150 shares worth $70.7M.
  • Avoro Capital Advisors added most to Cytokinetics in Q2 2026, an estimated $120M increase.
  • Avoro Capital Advisors's biggest Q2 2026 reduction was Revolution Medicines, cutting an estimated $6.93M.
  • Avoro Capital Advisors fully exited Apellis Pharmaceuticals in Q2 2026, selling an estimated $492M.
  • Avoro Capital Advisors's ten largest holdings make up 79% of its $11.1B portfolio in Q2 2026.
  • Avoro Capital Advisors opened 2 new positions and closed 8 in Q2 2026.
  • Avoro Capital Advisors's portfolio value rose 9.6% quarter-over-quarter to $11.1B.

Based on Avoro Capital Advisors's 13F filing for Q2 2026, filed 14 Aug 2026.