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APM

Avidity Partners Management Portfolio holdings

AUM $936M
1-Year Est. Return 195%
This Fund
S&P 500
This Quarter Est. Return
-8.9%
1 Year Est. Return
+195%
3 Year Est. Return
+460.87%
5 Year Est. Return
+815.5%
10 Year Est. Return
–
AUM
$525M
AUM Growth
-$493M
Cap. Flow
-$400M
Cap. Flow %
-76.25%
Top 10 Hldgs %
41.99%
Holding
85
New
22
Increased
4
Reduced
37
Closed
18

Top Buys

Rank Stock Value
1
BEAM icon
Beam Therapeutics
BEAM
+$18.6M
2
REGN icon
Regeneron Pharmaceuticals
REGN
+$11.7M
3
COR icon
Cencora
COR
+$9.87M
4
TEVA icon
Teva Pharmaceuticals
TEVA
+$8.59M
5
XBI icon
State Street SPDR S&P Biotech ETF
XBI
+$8.4M

Top Sells

Rank Stock Value
1
ISRG icon
Intuitive Surgical
ISRG
+$33.8M
2
MIRM icon
Mirum Pharmaceuticals
MIRM
+$29.5M
3
ACHC icon
Acadia Healthcare
ACHC
+$26.1M
4
DNTH icon
Dianthus Therapeutics
DNTH
+$25.4M
5
JAZZ icon
Jazz Pharmaceuticals
JAZZ
+$20.2M

Sector Composition

Rank Sector Weight
1 Healthcare 90.96%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
INCY icon
76
Incyte
INCY
$25.4B
– –
-129,600
Closed -$8.95M
ISRG icon
77
Intuitive Surgical
ISRG
$127B
– –
-64,800
Closed -$33.8M
KROS icon
78
Keros Therapeutics
KROS
$197M
– –
-210,000
Closed -$3.32M
KYMR icon
79
Kymera Therapeutics
KYMR
$8.66B
– –
-500,000
Closed -$20.1M
NMRA icon
80
CALL
Neumora Therapeutics
NMRA
$306M
– –
-150,000
Closed -$1.59M
ORIC icon
81
Oric Pharmaceuticals
ORIC
$1.17B
– –
-1,265,200
Closed -$10.2M
RCKT icon
82
Rocket Pharmaceuticals
RCKT
$343M
– –
-1,053,300
Closed -$13.2M
SGRY icon
83
Surgery Partners
SGRY
$2.15B
– –
-514,200
Closed -$10.9M
TMDX icon
84
Transmedics
TMDX
$2.7B
– –
-192,400
Closed -$12M
ITCI
85
DELISTED
Intra-Cellular Therapies Inc.
ITCI
– –
-97,000
Closed -$8.1M
1 2 3
4

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Avidity Partners Management's Q1 2025 Portfolio in Review

As of Q1 2025, Avidity Partners Management held 85 positions worth $525M, down 48% from $1.02B the previous quarter. Its ten largest holdings account for 42% of the portfolio.

Avidity Partners Management withdrew a net $400M in Q1 2025, closing 18 positions and reducing 37 holdings. Its most notable exit was Intuitive Surgical, an estimated $33.8M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 91% of assets, down from 99% a quarter earlier.

Against the trend, Avidity Partners Management opened a new position in Beam Therapeutics worth $13.9M.

  • Avidity Partners Management's largest Q1 2025 buy was Beam Therapeutics: 709,517 shares worth $13.9M.
  • Avidity Partners Management added most to Regeneron Pharmaceuticals in Q1 2025, an estimated $11.7M increase.
  • Avidity Partners Management's biggest Q1 2025 reduction was Mirum Pharmaceuticals, cutting an estimated $29.5M.
  • Avidity Partners Management fully exited Intuitive Surgical in Q1 2025, selling an estimated $33.8M.
  • Avidity Partners Management's ten largest holdings make up 42% of its $525M portfolio in Q1 2025.
  • Avidity Partners Management opened 22 new positions and closed 18 in Q1 2025.
  • Avidity Partners Management's portfolio value fell 48% quarter-over-quarter to $525M.

Based on Avidity Partners Management's 13F filing for Q1 2025, filed 15 May 2025.