American Century Companies Portfolio holdings
American Century Companies, Inc., founded in 1958 by James E. Stowers Jr. as Twentieth Century Mutual Funds and headquartered in Kansas City, Missouri, is a privately held investment management firm renowned for its focus on delivering investment results to clients while supporting medical research. Starting with just $100,000 from 24 shareholders, it rebranded to American Century Investments in 1997 and now manages hundreds of billions in assets across mutual funds, ETFs, and institutional portfolios, emphasizing no-load funds and a client-centric approach. The firm’s unique ownership structure sees over 40% of its profits funneled to the Stowers Institute for Medical Research, which it majority-owns, funding groundbreaking biomedical research, while Nomura Holdings holds a significant minority stake. With a global presence in cities like New York, London, and Hong Kong, and a workforce of around 1,400, American Century blends financial expertise with a mission to improve lives through both wealth creation and scientific advancement.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Amphenol
APH
|
+$460M |
| 2 |
Broadcom
AVGO
|
+$298M |
| 3 |
Sysco
SYY
|
+$225M |
| 4 |
MRSH
Marsh
MRSH
|
+$200M |
| 5 |
Ascendis Pharma A/S
ASND
|
+$186M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
NVIDIA
NVDA
|
+$573M |
| 2 |
Visa
V
|
+$465M |
| 3 |
Apple
AAPL
|
+$461M |
| 4 |
Alphabet (Google) Class A
GOOGL
|
+$363M |
| 5 |
Alphabet (Google) Class C
GOOG
|
+$358M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 26.8% |
| 2 | Financials | 13.6% |
| 3 | Consumer Discretionary | 12.52% |
| 4 | Industrials | 10.05% |
| 5 | Healthcare | 9.86% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
51
Boston Scientific
BSX
$74.5B
| $439M | 0.22% |
4,602,194
+603,088
| +15% | +$59.1M |
|
52
Lam Research
LRCX
$408B
| $436M | 0.22% |
2,545,199
-109,148
| -4% | -$17M |
|
|
MRSH
53
Marsh
MRSH
$90.1B
| $432M | 0.22% |
2,330,508
+1,070,029
| +85% | +$200M |
|
54
Wells Fargo
WFC
$269B
| $431M | 0.22% |
4,629,560
+1,375,695
| +42% | +$119M |
|
55
Salesforce
CRM
$158B
| $431M | 0.22% |
1,625,520
-908,567
| -36% | -$226M |
|
56
PepsiCo
PEP
$189B
| $430M | 0.22% |
2,997,509
-64,478
| -2% | -$9.47M |
|
57
Avantis US Equity ETF
AVUS
$14.4B
| $426M | 0.21% |
3,810,384
+239,346
| +7% | +$26.4M |
|
58
Regeneron Pharmaceuticals
REGN
$82.2B
| $426M | 0.21% |
551,487
-109,108
| -17% | -$74.1M |
|
59
Idexx Laboratories
IDXX
$45B
| $425M | 0.21% |
628,934
-76,224
| -11% | -$51.9M |
|
60
Micron Technology
MU
$1.03T
| $425M | 0.21% |
1,489,962
+189,232
| +15% | +$43.4M |
|
61
Williams Companies
WMB
$90.1B
| $411M | 0.21% |
6,835,433
+53,155
| +0.8% | +$3.21M |
|
62
Reinsurance Group of America
RGA
$16.1B
| $409M | 0.21% |
2,008,722
-360,335
| -15% | -$69.7M |
|
63
Walmart Inc
WMT
$923B
| $407M | 0.2% |
3,653,065
+1,351,786
| +59% | +$145M |
|
64
Cadence Design Systems
CDNS
$89B
| $405M | 0.2% |
1,296,275
-58,325
| -4% | -$19M |
|
65
Vertex Pharmaceuticals
VRTX
$133B
| $385M | 0.19% |
848,639
+399,446
| +89% | +$172M |
|
66
Baker Hughes
BKR
$63.8B
| $384M | 0.19% |
8,427,166
+2,267,012
| +37% | +$108M |
|
67
Cummins
CMI
$87.8B
| $382M | 0.19% |
747,492
-92,880
| -11% | -$43.4M |
|
68
CSX Corp
CSX
$92.8B
| $381M | 0.19% |
10,523,058
-441,399
| -4% | -$15.8M |
|
69
Interactive Brokers
IBKR
$41.5B
| $371M | 0.19% |
5,762,860
-190,787
| -3% | -$12.8M |
|
70
Kimberly-Clark
KMB
$36.2B
| $369M | 0.19% |
3,660,079
+1,125,649
| +44% | +$123M |
|
71
ServiceNow
NOW
$129B
| $368M | 0.19% |
2,403,443
+200,558
| +9% | +$34.4M |
|
72
KLA
KLAC
$272B
| $368M | 0.18% |
3,025,260
+762,920
| +34% | +$89.5M |
|
73
Caterpillar
CAT
$393B
| $366M | 0.18% |
638,692
-96,198
| -13% | -$53.5M |
|
74
Duke Energy
DUK
$96.3B
| $365M | 0.18% |
3,117,610
-161,121
| -5% | -$19.7M |
|
75
Cisco
CSCO
$488B
| $365M | 0.18% |
4,736,492
-579,736
| -11% | -$43M |
|
Similar funds
American Century Companies's Q4 2025 Portfolio in Review
As of Q4 2025, American Century Companies held 2,902 positions worth $199B, up 1.2% from $197B the previous quarter. Its ten largest holdings account for 27% of the portfolio.
American Century Companies's Q4 2025 filing shows 123 new, 1,653 increased, 947 reduced and 91 closed positions. Its largest new stake was Amrize Ltd: 2,173,524 shares worth $118M. The largest sale was NVIDIA, an estimated $573M.
By sector, the portfolio is most concentrated in Technology at 27% of assets, down from 28% a quarter earlier, followed by Financials and Consumer Discretionary.
- American Century Companies's largest Q4 2025 buy was Amrize Ltd: 2,173,524 shares worth $118M.
- American Century Companies added most to Amphenol in Q4 2025, an estimated $460M increase.
- American Century Companies's biggest Q4 2025 reduction was NVIDIA, cutting an estimated $573M.
- American Century Companies fully exited Premier in Q4 2025, selling an estimated $91.5M.
- American Century Companies's ten largest holdings make up 27% of its $199B portfolio in Q4 2025.
- American Century Companies opened 123 new positions and closed 91 in Q4 2025.
- American Century Companies's portfolio value rose 1.2% quarter-over-quarter to $199B.
Based on American Century Companies's 13F filing for Q4 2025, filed 13 Feb 2026.