American Century Companies Portfolio holdings
American Century Companies, Inc., founded in 1958 by James E. Stowers Jr. as Twentieth Century Mutual Funds and headquartered in Kansas City, Missouri, is a privately held investment management firm renowned for its focus on delivering investment results to clients while supporting medical research. Starting with just $100,000 from 24 shareholders, it rebranded to American Century Investments in 1997 and now manages hundreds of billions in assets across mutual funds, ETFs, and institutional portfolios, emphasizing no-load funds and a client-centric approach. The firm’s unique ownership structure sees over 40% of its profits funneled to the Stowers Institute for Medical Research, which it majority-owns, funding groundbreaking biomedical research, while Nomura Holdings holds a significant minority stake. With a global presence in cities like New York, London, and Hong Kong, and a workforce of around 1,400, American Century blends financial expertise with a mission to improve lives through both wealth creation and scientific advancement.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Amphenol
APH
|
+$460M |
| 2 |
Broadcom
AVGO
|
+$298M |
| 3 |
Sysco
SYY
|
+$225M |
| 4 |
MRSH
Marsh
MRSH
|
+$200M |
| 5 |
Ascendis Pharma A/S
ASND
|
+$186M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
NVIDIA
NVDA
|
+$573M |
| 2 |
Visa
V
|
+$465M |
| 3 |
Apple
AAPL
|
+$461M |
| 4 |
Alphabet (Google) Class A
GOOGL
|
+$363M |
| 5 |
Alphabet (Google) Class C
GOOG
|
+$358M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 26.8% |
| 2 | Financials | 13.6% |
| 3 | Consumer Discretionary | 12.52% |
| 4 | Industrials | 10.05% |
| 5 | Healthcare | 9.86% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
26
Palantir
PLTR
$411B
| $626M | 0.31% |
3,523,086
+833,242
| +31% | +$151M |
|
27
Cloudflare
NET
$111B
| $626M | 0.31% |
3,174,409
+243,352
| +8% | +$51.5M |
|
28
Becton Dickinson
BDX
$50B
| $607M | 0.31% |
3,129,651
-123,948
| -4% | -$23.6M |
|
29
Fair Isaac
FICO
$22.6B
| $594M | 0.3% |
351,273
+15,351
| +5% | +$26.4M |
|
30
Alnylam Pharmaceuticals
ALNY
$30B
| $591M | 0.3% |
1,485,161
-156,280
| -10% | -$69.2M |
|
31
Snowflake
SNOW
$115B
| $588M | 0.3% |
2,680,788
+575,863
| +27% | +$141M |
|
32
Norfolk Southern
NSC
$75.3B
| $586M | 0.29% |
2,028,929
-125,886
| -6% | -$36.4M |
|
33
Merck
MRK
$328B
| $565M | 0.28% |
5,368,610
+808,970
| +18% | +$75.9M |
|
34
Zscaler
ZS
$28.7B
| $540M | 0.27% |
2,401,772
-17,178
| -0.7% | -$4.85M |
|
35
Verizon
VZ
$195B
| $532M | 0.27% |
13,059,335
+80,336
| +0.6% | +$3.26M |
|
36
Gilead Sciences
GILD
$168B
| $527M | 0.26% |
4,293,884
+488,335
| +13% | +$59.3M |
|
37
Vertiv
VRT
$111B
| $518M | 0.26% |
3,195,264
-236,496
| -7% | -$41.1M |
|
38
TJX Companies
TJX
$169B
| $514M | 0.26% |
3,348,511
-233,319
| -7% | -$34.5M |
|
39
Datadog
DDOG
$86.5B
| $496M | 0.25% |
3,648,860
-54,796
| -1% | -$8.66M |
|
40
American Express
AXP
$232B
| $495M | 0.25% |
1,338,389
+228,932
| +21% | +$81.9M |
|
41
Truist Financial
TFC
$64.3B
| $488M | 0.25% |
9,921,542
-1,585,690
| -14% | -$73M |
|
42
Alibaba
BABA
$300B
| $483M | 0.24% |
3,293,118
+305,579
| +10% | +$49.8M |
|
43
Enterprise Products Partners
EPD
$81.9B
| $476M | 0.24% |
14,855,077
-2,213,727
| -13% | -$70M |
|
44
US Bancorp
USB
$101B
| $474M | 0.24% |
8,888,512
-1,556,195
| -15% | -$76.5M |
|
45
Medtronic
MDT
$116B
| $466M | 0.23% |
4,854,208
-949,306
| -16% | -$92.2M |
|
46
S&P Global
SPGI
$121B
| $463M | 0.23% |
886,577
+137,852
| +18% | +$68.2M |
|
47
Kenvue
KVUE
$36.5B
| $461M | 0.23% |
26,737,523
-10,309,137
| -28% | -$169M |
|
48
Insulet
PODD
$10.1B
| $450M | 0.23% |
1,584,424
+177,561
| +13% | +$55.5M |
|
49
Packaging Corp of America
PKG
$22.8B
| $445M | 0.22% |
2,156,474
+232,424
| +12% | +$47.3M |
|
50
Zimmer Biomet
ZBH
$18.7B
| $442M | 0.22% |
4,915,237
-261,459
| -5% | -$24.8M |
|
Similar funds
American Century Companies's Q4 2025 Portfolio in Review
As of Q4 2025, American Century Companies held 2,902 positions worth $199B, up 1.2% from $197B the previous quarter. Its ten largest holdings account for 27% of the portfolio.
American Century Companies's Q4 2025 filing shows 123 new, 1,653 increased, 947 reduced and 91 closed positions. Its largest new stake was Amrize Ltd: 2,173,524 shares worth $118M. The largest sale was NVIDIA, an estimated $573M.
By sector, the portfolio is most concentrated in Technology at 27% of assets, down from 28% a quarter earlier, followed by Financials and Consumer Discretionary.
- American Century Companies's largest Q4 2025 buy was Amrize Ltd: 2,173,524 shares worth $118M.
- American Century Companies added most to Amphenol in Q4 2025, an estimated $460M increase.
- American Century Companies's biggest Q4 2025 reduction was NVIDIA, cutting an estimated $573M.
- American Century Companies fully exited Premier in Q4 2025, selling an estimated $91.5M.
- American Century Companies's ten largest holdings make up 27% of its $199B portfolio in Q4 2025.
- American Century Companies opened 123 new positions and closed 91 in Q4 2025.
- American Century Companies's portfolio value rose 1.2% quarter-over-quarter to $199B.
Based on American Century Companies's 13F filing for Q4 2025, filed 13 Feb 2026.