American Century Companies Portfolio holdings
American Century Companies, Inc., founded in 1958 by James E. Stowers Jr. as Twentieth Century Mutual Funds and headquartered in Kansas City, Missouri, is a privately held investment management firm renowned for its focus on delivering investment results to clients while supporting medical research. Starting with just $100,000 from 24 shareholders, it rebranded to American Century Investments in 1997 and now manages hundreds of billions in assets across mutual funds, ETFs, and institutional portfolios, emphasizing no-load funds and a client-centric approach. The firm’s unique ownership structure sees over 40% of its profits funneled to the Stowers Institute for Medical Research, which it majority-owns, funding groundbreaking biomedical research, while Nomura Holdings holds a significant minority stake. With a global presence in cities like New York, London, and Hong Kong, and a workforce of around 1,400, American Century blends financial expertise with a mission to improve lives through both wealth creation and scientific advancement.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Amphenol
APH
|
+$460M |
| 2 |
Broadcom
AVGO
|
+$298M |
| 3 |
Sysco
SYY
|
+$225M |
| 4 |
MRSH
Marsh
MRSH
|
+$200M |
| 5 |
Ascendis Pharma A/S
ASND
|
+$186M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
NVIDIA
NVDA
|
+$573M |
| 2 |
Visa
V
|
+$465M |
| 3 |
Apple
AAPL
|
+$461M |
| 4 |
Alphabet (Google) Class A
GOOGL
|
+$363M |
| 5 |
Alphabet (Google) Class C
GOOG
|
+$358M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 26.8% |
| 2 | Financials | 13.6% |
| 3 | Consumer Discretionary | 12.52% |
| 4 | Industrials | 10.05% |
| 5 | Healthcare | 9.86% |
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American Century Companies's Q4 2025 Portfolio in Review
As of Q4 2025, American Century Companies held 2,902 positions worth $199B, up 1.2% from $197B the previous quarter. Its ten largest holdings account for 27% of the portfolio.
American Century Companies's Q4 2025 filing shows 123 new, 1,653 increased, 947 reduced and 91 closed positions. Its largest new stake was Amrize Ltd: 2,173,524 shares worth $118M. The largest sale was NVIDIA, an estimated $573M.
By sector, the portfolio is most concentrated in Technology at 27% of assets, down from 28% a quarter earlier, followed by Financials and Consumer Discretionary.
- American Century Companies's largest Q4 2025 buy was Amrize Ltd: 2,173,524 shares worth $118M.
- American Century Companies added most to Amphenol in Q4 2025, an estimated $460M increase.
- American Century Companies's biggest Q4 2025 reduction was NVIDIA, cutting an estimated $573M.
- American Century Companies fully exited Premier in Q4 2025, selling an estimated $91.5M.
- American Century Companies's ten largest holdings make up 27% of its $199B portfolio in Q4 2025.
- American Century Companies opened 123 new positions and closed 91 in Q4 2025.
- American Century Companies's portfolio value rose 1.2% quarter-over-quarter to $199B.
Based on American Century Companies's 13F filing for Q4 2025, filed 13 Feb 2026.