American Century Companies Portfolio holdings
American Century Companies, Inc., founded in 1958 by James E. Stowers Jr. as Twentieth Century Mutual Funds and headquartered in Kansas City, Missouri, is a privately held investment management firm renowned for its focus on delivering investment results to clients while supporting medical research. Starting with just $100,000 from 24 shareholders, it rebranded to American Century Investments in 1997 and now manages hundreds of billions in assets across mutual funds, ETFs, and institutional portfolios, emphasizing no-load funds and a client-centric approach. The firm’s unique ownership structure sees over 40% of its profits funneled to the Stowers Institute for Medical Research, which it majority-owns, funding groundbreaking biomedical research, while Nomura Holdings holds a significant minority stake. With a global presence in cities like New York, London, and Hong Kong, and a workforce of around 1,400, American Century blends financial expertise with a mission to improve lives through both wealth creation and scientific advancement.
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Amphenol
APH
|
+$460M |
| 2 |
Broadcom
AVGO
|
+$298M |
| 3 |
Sysco
SYY
|
+$225M |
| 4 |
MRSH
Marsh
MRSH
|
+$200M |
| 5 |
Ascendis Pharma A/S
ASND
|
+$186M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
NVIDIA
NVDA
|
+$573M |
| 2 |
Visa
V
|
+$465M |
| 3 |
Apple
AAPL
|
+$461M |
| 4 |
Alphabet (Google) Class A
GOOGL
|
+$363M |
| 5 |
Alphabet (Google) Class C
GOOG
|
+$358M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 26.8% |
| 2 | Financials | 13.6% |
| 3 | Consumer Discretionary | 12.52% |
| 4 | Industrials | 10.05% |
| 5 | Healthcare | 9.86% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
2576
Janux Therapeutics
JANX
$978M
| $382K | ﹤0.01% |
27,691
+8,738
| +46% | +$206K |
|
|
ARDT
2577
Ardent Health
ARDT
$1.55B
| $379K | ﹤0.01% |
42,873
+2,689
| +7% | +$31.1K |
|
2578
First Western Financial
MYFW
$309M
| $377K | ﹤0.01% |
14,078
| – | – |
|
2579
Brown-Forman Class A
BF.A
$13.1B
| $372K | ﹤0.01% |
14,146
+3,011
| +27% | +$84K |
|
2580
Patria Investments
PAX
$1.88B
| $372K | ﹤0.01% |
23,393
-279
| -1% | -$4.18K |
|
2581
Biglari Holdings Class B
BH
$1.22B
| $371K | ﹤0.01% |
1,116
| – | – |
|
2582
WEX
WEX
$6.78B
| $371K | ﹤0.01% |
2,487
-1,383
| -36% | -$208K |
|
|
BBNX
2583
Beta Bionics
BBNX
$813M
| $366K | ﹤0.01% |
+12,024
| New | +$321K |
|
2584
CF Bankshares
CFBK
$235M
| $366K | ﹤0.01% |
+14,677
| New | +$350K |
|
2585
James Hardie Industries
JHX
$17.9B
| $364K | ﹤0.01% |
17,544
+1,672
| +11% | +$33.5K |
|
2586
Sagimet Biosciences
SGMT
$577M
| $363K | ﹤0.01% |
61,383
+2,924
| +5% | +$21K |
|
2587
Neurogene
NGNE
$713M
| $362K | ﹤0.01% |
17,560
+3,929
| +29% | +$97.8K |
|
2588
Clean Energy Fuels
CLNE
$395M
| $361K | ﹤0.01% |
172,023
+78,726
| +84% | +$193K |
|
2589
Lifeway Foods
LWAY
$377M
| $361K | ﹤0.01% |
14,881
-17,733
| -54% | -$435K |
|
2590
EverCommerce
EVCM
$1.79B
| $359K | ﹤0.01% |
29,608
| – | – |
|
2591
Farmers & Merchants Bancorp
FMAO
$486M
| $354K | ﹤0.01% |
14,331
| – | – |
|
2592
Asana
ASAN
$2.28B
| $353K | ﹤0.01% |
25,758
-2,383
| -8% | -$32.8K |
|
|
AEBI
2593
Aebi Schmidt Holding AG
AEBI
$1.06B
| $353K | ﹤0.01% |
27,913
-3,886
| -12% | -$46.4K |
|
2594
Information Services Group
III
$250M
| $353K | ﹤0.01% |
61,014
+10,224
| +20% | +$57.4K |
|
2595
Domino's
DPZ
$11.6B
| $353K | ﹤0.01% |
846
+303
| +56% | +$126K |
|
2596
Iovance Biotherapeutics
IOVA
$2.95B
| $352K | ﹤0.01% |
129,088
+100,624
| +354% | +$233K |
|
2597
PTC Therapeutics
PTCT
$6.01B
| $349K | ﹤0.01% |
4,589
-13,568
| -75% | -$986K |
|
2598
CS Disco
LAW
$297M
| $347K | ﹤0.01% |
44,699
+5,090
| +13% | +$35.9K |
|
|
RAPT
2599
DELISTED
RAPT Therapeutics
RAPT
| $346K | ﹤0.01% |
+10,218
| New | +$317K |
|
2600
Tyler Technologies
TYL
$13.5B
| $345K | ﹤0.01% |
759
+125
| +20% | +$59.5K |
|
Similar funds
American Century Companies's Q4 2025 Portfolio in Review
As of Q4 2025, American Century Companies held 2,902 positions worth $199B, up 1.2% from $197B the previous quarter. Its ten largest holdings account for 27% of the portfolio.
American Century Companies's Q4 2025 filing shows 123 new, 1,653 increased, 947 reduced and 91 closed positions. Its largest new stake was Amrize Ltd: 2,173,524 shares worth $118M. The largest sale was NVIDIA, an estimated $573M.
By sector, the portfolio is most concentrated in Technology at 27% of assets, down from 28% a quarter earlier, followed by Financials and Consumer Discretionary.
- American Century Companies's largest Q4 2025 buy was Amrize Ltd: 2,173,524 shares worth $118M.
- American Century Companies added most to Amphenol in Q4 2025, an estimated $460M increase.
- American Century Companies's biggest Q4 2025 reduction was NVIDIA, cutting an estimated $573M.
- American Century Companies fully exited Premier in Q4 2025, selling an estimated $91.5M.
- American Century Companies's ten largest holdings make up 27% of its $199B portfolio in Q4 2025.
- American Century Companies opened 123 new positions and closed 91 in Q4 2025.
- American Century Companies's portfolio value rose 1.2% quarter-over-quarter to $199B.
Based on American Century Companies's 13F filing for Q4 2025, filed 13 Feb 2026.