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Alyeska Investment Group Portfolio holdings
AUM
$35.4B
1-Year Est. Return
33.54%
This Fund
S&P 500
This Quarter
Est. Return
+2.82%
1 Year Est. Return
+33.54%
3 Year Est. Return
+101.08%
5 Year Est. Return
+102.29%
10 Year Est. Return
+544.32%
AUM
$35.4B
AUM Growth
+$2.35B
(+7.1%)
Cap. Flow
+$2.2B
Cap. Flow
% of AUM
6.21%
Top 10 Holdings %
Top 10 Hldgs %
25.61%
Holding
774
New
196
Increased
195
Reduced
148
Closed
199
Top Buys
| Rank | Stock | Value |
|---|---|---|
| 1 |
Amazon
AMZN
|
+$439M |
| 2 |
DoorDash
DASH
|
+$385M |
| 3 |
Microsoft
MSFT
|
+$346M |
| 4 |
Boeing
BA
|
+$329M |
| 5 |
Broadcom
AVGO
|
+$324M |
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
Apple
AAPL
|
+$928M |
| 2 |
Salesforce
CRM
|
+$590M |
| 3 |
NVIDIA
NVDA
|
+$444M |
| 4 |
Tesla
TSLA
|
+$358M |
| 5 |
Bank of America
BAC
|
+$353M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 19.01% |
| 2 | Consumer Discretionary | 16.33% |
| 3 | Healthcare | 11.24% |
| 4 | Industrials | 11.17% |
| 5 | Real Estate | 7.17% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
501
TriSalus Life Sciences
TLSI
$344M
| $2.84M | 0.01% |
407,500
-150,000
| -27% | -$840K |
|
502
Gossamer Bio
GOSS
$86.1M
| $2.82M | 0.01% |
909,087
-1,000,000
| -52% | -$2.85M |
|
503
Denison Mines
DNN
$2.95B
| $2.66M | 0.01% |
1,000,400
| – | – |
|
|
KMTS
504
Kestra Medical Technologies
KMTS
$1.66B
| $2.65M | 0.01% |
+100,000
| New | +$2.58M |
|
505
ESS Tech
GWH
$17.1M
| $2.63M | 0.01% |
+1,400,000
| New | +$4.45M |
|
|
DFDV
506
DeFi Development Corp
DFDV
$86.1M
| $2.62M | 0.01% |
518,522
-163,276
| -24% | -$1.5M |
|
507
Monopar Therapeutics
MNPR
$779M
| $2.61M | 0.01% |
40,000
+27,785
| +227% | +$2.27M |
|
508
GH Research
GHRS
$2.03B
| $2.6M | 0.01% |
204,975
| – | – |
|
|
NUVL
509
DELISTED
Nuvalent
NUVL
| $2.57M | 0.01% |
25,533
-75,533
| -75% | -$7.45M |
|
|
KEEL
510
Keel Infrastructure Corp
KEEL
$2.05B
| $2.54M | 0.01% |
+1,079,700
| New | +$3.7M |
|
511
Unusual Machines
UMAC
$1.36B
| $2.52M | 0.01% |
+197,912
| New | +$2.32M |
|
512
Context Therapeutics
CNTX
$41.6M
| $2.45M | 0.01% |
1,663,355
| – | – |
|
513
Stoke Therapeutics
STOK
$2.08B
| $2.38M | 0.01% |
+75,000
| New | +$2.25M |
|
|
ACOG
514
Alpha Cognition
ACOG
$194M
| $2.37M | 0.01% |
+365,000
| New | +$2.31M |
|
|
BNC
515
CEA Industries
BNC
$99.2M
| $2.34M | 0.01% |
364,771
-432,264
| -54% | -$3.03M |
|
|
IVA
516
Inventiva
IVA
$1.12B
| $2.33M | 0.01% |
+500,000
| New | +$2.32M |
|
517
Dragonfly Energy
DFLI
$18.8M
| $2.29M | 0.01% |
+744,422
| New | +$6.83M |
|
518
Plexus
PLXS
$7.16B
| $2.25M | 0.01% |
+15,289
| New | +$2.24M |
|
519
IN8bio
INAB
$9.61M
| $2.23M | 0.01% |
957,484
+875,000
| +1,061% | +$1.66M |
|
520
Veru
VERU
$44.5M
| $2.14M | 0.01% |
+1,000,000
| New | +$2.98M |
|
521
ProPetro Holding
PUMP
$1.43B
| $2.13M | 0.01% |
+224,461
| New | +$1.95M |
|
|
VOXR
522
Vox Royalty Corp
VOXR
$354M
| $2.01M | 0.01% |
425,000
| – | – |
|
523
Acumen Pharmaceuticals
ABOS
$176M
| $1.98M | 0.01% |
939,603
| – | – |
|
524
Protara Therapeutics
TARA
$231M
| $1.87M | 0.01% |
+350,000
| New | +$1.95M |
|
525
Casey's General Stores
CASY
$31.6B
| $1.78M | 0.01% |
+3,229
| New | +$1.78M |
|
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Alyeska Investment Group's Q4 2025 Portfolio in Review
As of Q4 2025, Alyeska Investment Group held 774 positions worth $35.4B, up 7.1% from $33.1B the previous quarter. Its ten largest holdings account for 26% of the portfolio.
Alyeska Investment Group deployed $2.2B of net new capital in Q4 2025, opening 196 new positions and adding to 195 existing holdings. Its largest new stake was DoorDash: 1,643,096 shares worth $372M.
By sector, the portfolio is most concentrated in Technology at 19% of assets, down from 24% a quarter earlier, followed by Consumer Discretionary and Healthcare.
On the sell side, the largest reduction was Twilio, an estimated $289M trimmed.
- Alyeska Investment Group's largest Q4 2025 buy was DoorDash: 1,643,096 shares worth $372M.
- Alyeska Investment Group added most to Amazon in Q4 2025, an estimated $439M increase.
- Alyeska Investment Group's biggest Q4 2025 reduction was Twilio, cutting an estimated $289M.
- Alyeska Investment Group fully exited Apple in Q4 2025, selling an estimated $928M.
- Alyeska Investment Group's ten largest holdings make up 26% of its $35.4B portfolio in Q4 2025.
- Alyeska Investment Group opened 196 new positions and closed 199 in Q4 2025.
- Alyeska Investment Group's portfolio value rose 7.1% quarter-over-quarter to $35.4B.
Based on Alyeska Investment Group's 13F filing for Q4 2025, filed 13 Feb 2026.