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Alphabet Inc Portfolio holdings
AUM
$99.1B
1-Year Est. Return
124.46%
This Fund
S&P 500
This Quarter
Est. Return
+32.02%
1 Year Est. Return
+124.46%
3 Year Est. Return
+326.82%
5 Year Est. Return
+231.24%
10 Year Est. Return
+1,201.66%
AUM
$2.58B
AUM Growth
+$171M
(+7.1%)
Cap. Flow
-$313M
Cap. Flow
% of AUM
-12.12%
Top 10 Holdings %
Top 10 Hldgs %
92.81%
Holding
37
New
–
Increased
–
Reduced
3
Closed
8
Top Buys
No buys this quarter
Top Sells
| Rank | Stock | Value |
|---|---|---|
| 1 |
MTSR
Metsera Inc
MTSR
|
+$198M |
| 2 |
Revolution Medicines
RVMD
|
+$51.7M |
| 3 |
MAZE
Maze Therapeutics
MAZE
|
+$35.2M |
| 4 |
Monte Rosa Therapeutics
GLUE
|
+$9.69M |
| 5 |
Dianthus Therapeutics
DNTH
|
+$8.21M |
Sector Composition
| Rank | Sector | Weight |
|---|---|---|
| 1 | Technology | 49.93% |
| 2 | Healthcare | 25.65% |
| 3 | Industrials | 24.42% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Change in Stake | Capital Flow | |
|---|---|---|---|---|---|---|
26
Tenaya Therapeutics
TNYA
$164M
| $650K | 0.03% |
915,705
| – | – |
|
27
Quince Therapeutics
QNCX
$33M
| $634K | 0.02% |
946
| – | – |
|
28
Fulcrum Therapeutics
FULC
$283M
| $161K | 0.01% |
14,262
| – | – |
|
29
Repligen
RGEN
$9.45B
| $62.8K | ﹤0.01% |
383
| – | – |
|
30
Alector
ALEC
$228M
| – | – |
-175,866
| Closed | -$521K |
|
|
BRNS
31
Barinthus Biotherapeutics
BRNS
$24.5M
| – | – |
-1,513,644
| Closed | -$1.89M |
|
|
32
Dianthus Therapeutics
DNTH
$6.13B
| – | – |
-208,697
| Closed | -$8.21M |
|
33
Foghorn Therapeutics
FHTX
$385M
| – | – |
-500,901
| Closed | -$2.45M |
|
34
TScan Therapeutics
TCRX
$52.3M
| – | – |
-1,077,080
| Closed | -$1.96M |
|
35
Taysha Gene Therapies
TSHA
$1.92B
| – | – |
-640,882
| Closed | -$2.1M |
|
36
Fractyl Health
GUTS
$105M
| – | – |
-662,584
| Closed | -$1.05M |
|
|
MTSR
37
DELISTED
Metsera Inc
MTSR
| – | – |
-3,783,528
| Closed | -$198M |
|
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Alphabet Inc's Q4 2025 Portfolio in Review
As of Q4 2025, Alphabet Inc held 37 positions worth $2.58B, up 7.1% from $2.41B the previous quarter. Its ten largest holdings account for 93% of the portfolio.
Alphabet Inc withdrew a net $313M in Q4 2025, closing 8 positions and reducing 3 holdings. Its most notable exit was Metsera Inc, an estimated $198M position sold in full.
By sector, the portfolio is most concentrated in Technology at 50% of assets, up from 47% a quarter earlier, followed by Healthcare and Industrials.
- Alphabet Inc's biggest Q4 2025 reduction was Revolution Medicines, cutting an estimated $51.7M.
- Alphabet Inc fully exited Metsera Inc in Q4 2025, selling an estimated $198M.
- Alphabet Inc's ten largest holdings make up 93% of its $2.58B portfolio in Q4 2025.
- Alphabet Inc opened 0 new positions and closed 8 in Q4 2025.
- Alphabet Inc's portfolio value rose 7.1% quarter-over-quarter to $2.58B.
Based on Alphabet Inc's 13F filing for Q4 2025, filed 13 Feb 2026.