Adage Capital Partners’s Five Prime Therapeutics, Inc. FPRX Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2021 Q1	–	Sell	-900,000	Closed	-$15.3M	–	1088
2020 Q4	$15.3M	Buy	+900,000	New	+$11.3M	0.03%	494
2020 Q2	–	Sell	-250,000	Closed	-$568K	–	820
2020 Q1	$568K	Hold	250,000	–	–	﹤0.01%	696
2019 Q4	$1.15M	Sell	250,000 -1,000,000	-80%	-$3.96M	﹤0.01%	677
2019 Q3	$4.84M	Buy	1,250,000 +50,000	+4%	+$274K	0.01%	630
2019 Q2	$7.24M	Buy	1,200,000 +50,000	+4%	+$478K	0.02%	567
2019 Q1	$15.4M	Buy	1,150,000 +250,000	+28%	+$2.85M	0.04%	444
2018 Q4	$8.37M	Buy	900,000 +252,000	+39%	+$3M	0.02%	538
2018 Q3	$9.02M	Sell	648,000 -42,000	-6%	-$625K	0.02%	561
2018 Q2	$10.9M	Sell	690,000 -110,000	-14%	-$1.92M	0.03%	545
2018 Q1	$13.7M	Sell	800,000 -500,000	-38%	-$9.75M	0.03%	492
2017 Q4	$28.5M	Sell	1,300,000 -1,132,700	-47%	-$36.4M	0.06%	329
2017 Q3	$99.5M	Sell	2,432,700 -61,300	-2%	-$1.92M	0.24%	110
2017 Q2	$75.1M	Sell	2,494,000 -96,000	-4%	-$3M	0.18%	159
2017 Q1	$93.6M	Buy	2,590,000 +690,000	+36%	+$30.4M	0.24%	117
2016 Q4	$95.2M	Sell	1,900,000 -225,100	-11%	-$11.8M	0.26%	102
2016 Q3	$112M	Sell	2,125,100 -241,900	-10%	-$11.6M	0.31%	85
2016 Q2	$97.9M	Sell	2,367,000 -233,000	-9%	-$10.1M	0.27%	106
2016 Q1	$106M	Buy	2,600,000 +275,000	+12%	+$9.45M	0.29%	98
2015 Q4	$96.5M	Sell	2,325,000 -339,949	-13%	-$11.4M	0.25%	118
2015 Q3	$41M	Buy	2,664,949 +701,457	+36%	+$15.1M	0.11%	231
2015 Q2	$48.8M	Buy	1,963,492 +350,208	+22%	+$7.8M	0.12%	225
2015 Q1	$36.9M	Buy	1,613,284 +693,402	+75%	+$17.5M	0.09%	285
2014 Q4	$24.8M	Buy	919,882 +419,882	+84%	+$7.23M	0.06%	360
2014 Q3	$5.87M	Buy	500,000 +412,597	+472%	+$5.21M	0.01%	600
2014 Q2	$1.36M	Buy	+87,403	New	+$1.25M	﹤0.01%	666