CARGO TherapeuticsCRGX
About: Cargo Therapeutics Inc is a clinical-stage biotechnology company positioned to advance next generation, potentially curative cell therapies for cancer patients. It programs, platforms, and manufacturing are designed to directly address the limitations of approved chimeric antigen receptor (CAR) T-cell therapies. Its product includes CRG-023, an investigational tri-specific CAR T designed to address several known causes of relapse associated with existing CAR T-cell therapies such as loss of tumor antigen expression, loss of co-stimulation (e.g., via CD58/CD2 signaling) and T cell exhaustion. CRG-023 is designed to target the B-cell lineage antigens (CD19, CD20, CD22) via tri-cistronic expression of three distinct CARs from a single lentiviral vector.
Employees: 167
Fund manager confidence
Based on 2025 Q1 regulatory disclosures by fund managers ($100M+ AUM)
555% more call options, than puts
Call options by funds: $190K | Put options by funds: $29K
64% more first-time investments, than exits
New positions opened: 41 | Existing positions closed: 25
15% more funds holding
Funds holding: 99 [Q4 2024] → 114 (+15) [Q1 2025]
14% less funds holding in top 10
Funds holding in top 10: 7 [Q4 2024] → 6 (-1) [Q1 2025]
17% less repeat investments, than reductions
Existing positions increased: 25 | Existing positions reduced: 30
17.17% less ownership
Funds ownership: 117.7% [Q4 2024] → 100.53% (-17.17%) [Q1 2025]
76% less capital invested
Capital invested by funds: $781M [Q4 2024] → $188M (-$593M) [Q1 2025]
Research analyst outlook
1 Wall Street Analyst provided 1 year price targets over the past 3 months
1 analyst rating
Jefferies Michael Yee | 9%upside $5 | Hold Maintained | 8 Jul 2025 |
Financial journalist opinion
Based on 6 articles about CRGX published over the past 30 days









